Application | Comment | Organism |
---|---|---|
medicine | monoclonal antibody MAb 5C4 is the only anti-fragment C (heavy chain) antibody which is capable of blocking the binding of recombinant fragment C to GT1b gangliosides | Clostridium tetani |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | dependent on | Clostridium tetani |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
vesicle associated membrane protein-2 + H2O | Clostridium tetani | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium tetani | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
vesicle associated membrane protein-2 + H2O | - |
Clostridium tetani | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TeNT | - |
Clostridium tetani |
Tetanus neurotoxin | - |
Clostridium tetani |
tetanus toxin | - |
Clostridium tetani |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme cleaves a neuronal soluble N-ethylmaleimide-sensitive attachment receptor protein, leading to the blockade of inhibitory neurotransmitter release and subsequent generalized muscular spasm | Clostridium tetani |