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Literature summary for 3.4.24.63 extracted from
- Downregulated expression in high IgA (HIGA) mice and the renal protective role of meprinbeta (2008), Life Sci., 82, 899-908.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | results suggest that meprinbeta may play a protective role against the progression of renal injury through the degradation of extracellular matrix and bioactive peptides | Mus musculus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| analysis of expression level of meprinbeta in high IgA mouse (time dependent) | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| actinonin | in vivo inhibition of meprins by actinonin exacerbates some parameters of renal injury in mice afflicted with anti-glomerular basement membrane antibody-associated nephritis | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
high IgA mouse used as model of human IgA nephropathy | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| renal glomerulus | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Meprin b | analysis of gene encoding subunit meprinbeta | Mus musculus |
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Release 2023.1 (January 2023)
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