Cloned (Comment) | Organism |
---|---|
expression of mepbetaDELTATM, meprin beta coding region lacking the transmembrane and intracellular domains with V5 and hexahistidine C-terminal tags (termed as mepbetaDELTATM) in HEK-293F cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | meprin B may play an important role in activation of the proinflammatory cytokine in various pathophysiological conditions | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16820 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
interleukin-1beta precursor + H2O | proteolytic cleavage to a biologically active form | Homo sapiens | interleukin-1beta + interleukin-1beta propeptide | - |
? | |
additional information | meprin B may play an important role in activation of the proinflammatory cytokine in various pathophysiological conditions | Homo sapiens | ? | - |
? |