Any feedback?
Literature summary for 3.4.24.63 extracted from
- Generation of biologically active interleukin-1beta by meprin B (2005), Cytokine, 31, 394-403.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of mepbetaDELTATM, meprin beta coding region lacking the transmembrane and intracellular domains with V5 and hexahistidine C-terminal tags (termed as mepbetaDELTATM) in HEK-293F cells | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | meprin B may play an important role in activation of the proinflammatory cytokine in various pathophysiological conditions | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q16820 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| interleukin-1beta precursor + H2O | proteolytic cleavage to a biologically active form | Homo sapiens | interleukin-1beta + interleukin-1beta propeptide | - |
? | |
| additional information | meprin B may play an important role in activation of the proinflammatory cytokine in various pathophysiological conditions | Homo sapiens | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
