Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cys-Lys-Gly-Gly-Lys-Arg-Ala-Val-Lys-Cys | - |
Bos taurus | |
Leu-Gly-Gly-Lys-Arg-Ala-Val-Lys-Asp | - |
Bos taurus | |
additional information | pro-oxytocin/neurophysin derived peptides (overview) | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | metalloendopeptidase | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypophysis | pituitary neurosecretory granule | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | overview | Bos taurus | ? | - |
? | |
additional information | relationship between structure and enzyme action | Bos taurus | ? | - |
? | |
additional information | specificity depends on the organization of a beta-turn-alpha-helix of nine or more residues containing the basic amino acid doublet near the centre | Bos taurus | ? | - |
? | |
additional information | No substrates are oxytocin/neurophysin | Bos taurus | ? | - |
? | |
additional information | structural requirements of the substrate peptides (pro-OT/Np-model) | Bos taurus | ? | - |
? | |
Pro-oxytocin/neurophysin(1-20) + H2O | obtained by hemisynthesis | Bos taurus | Pro-oxytocin/neurophysin(1-12) + pro-oxytocin/neurophysin(13-20) | i.e. peptide II (i.e. oxytocinGly10Lys11Arg12 and peptide III) | ? | |
Pro-oxytocin/neurophysin(1-20) + H2O | strictly selective for basic amino acid doublet Lys11-Arg12, cleavage site: Arg12-Ala13 | Bos taurus | Pro-oxytocin/neurophysin(1-12) + pro-oxytocin/neurophysin(13-20) | i.e. peptide II (i.e. oxytocinGly10Lys11Arg12 and peptide III) | ? | |
Pro-oxytocin/neurophysin(1-20) + H2O | i.e. model substrate peptide I | Bos taurus | Pro-oxytocin/neurophysin(1-12) + pro-oxytocin/neurophysin(13-20) | i.e. peptide II (i.e. oxytocinGly10Lys11Arg12 and peptide III) | ? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Bos taurus |