Activating Compound | Comment | Organism | Structure |
---|---|---|---|
p42IP4 | p42IP4 (centaurin alpha1) enhances the enzymatic activity of NRD 3-4 times. | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SH-SY5Y cell | NRD is expressed in the neurites of RA-stimulated SHSY5Y cells, and localized in vesicular structures | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Abz-GGGFLRRVGQ-EDDnp + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nardilysin | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
34 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | differentiation of SH-SY5Y cells by stimulation with 10 microM retinoic acid (RA) results in upregulation of NRD protein levels, with a 6fold rise after 15 days | up |