Application | Comment | Organism |
---|---|---|
medicine | russellysin is able to inhibit platelet aggregation but the RGD sequence is replaced by Arg-Asp-Glu in the corresponding region | Protobothrops mucrosquamatus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
Protobothrops mucrosquamatus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | essential for proteolytic activity | Protobothrops mucrosquamatus | |
Zn2+ | essential for proteolytic activity | Protobothrops mucrosquamatus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
18000 | - |
light chain | Protobothrops mucrosquamatus |
21000 | - |
light chain | Protobothrops mucrosquamatus |
59000 | - |
heavy chain, consists of metalloproteinase, disintegrin and cysteine-rich domains | Protobothrops mucrosquamatus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Protobothrops mucrosquamatus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Protobothrops mucrosquamatus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Protobothrops mucrosquamatus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
coagulation factor IX + H2O | cleavage at the Arg-Xaa bond | Protobothrops mucrosquamatus | ? | - |
? | |
coagulation factor X + H2O | cleavage at the Arg-Ile bond | Protobothrops mucrosquamatus | ? | - |
? | |
additional information | no action on the B chain of insulin | Protobothrops mucrosquamatus | ? | - |
? | |
o-aminobenzoyl-Gly-Phe-Arg-Leu-Leu-2,4-dinitroanilinoethylamide + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
protein C + H2O | cleavage at the Arg-Xaa bond | Protobothrops mucrosquamatus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Russell`s viper venom coagulation factor X-activating enzyme | - |
Protobothrops mucrosquamatus |
RVV-X | - |
Protobothrops mucrosquamatus |