Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.56 extracted from

  • Miller, B.C.; Eckman, E.A.; Sambamurti, K.; Dobbs, N.; Chow, K.M.; Eckman, C.B.; Hersh, L.B.; Thiele, D.L.
    Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo (2003), Proc. Natl. Acad. Sci. USA, 100, 6221-6226.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.56

Application

Application Comment Organism
medicine inverse correlation between insulysin activity levels and brain Abeta peptide levels suggest that modulation of insulysin activity may alter the risk for Alzheimer's disease Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc metalloprotease Rattus norvegicus
Zn2+ zinc metalloprotease Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
110000 115000 SDS-PAGE Mus musculus
113000
-
 Western blot Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q8CGB9 mouse, Omnibank B6.129
-
Rattus norvegicus
-
 rat
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid-beta peptide + H2O
-
 Rattus norvegicus ?
-
 ?
amyloid-beta peptide + H2O
-
 Mus musculus ?
-
 ?
beta-endorphin + H2O
-
 Rattus norvegicus gamma-endorphin + ?
-
 ?
beta-endorphin + H2O
-
 Mus musculus gamma-endorphin + ?
-
 ?
insulin + H2O
-
 Rattus norvegicus ?
-
 ?
insulin + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
IDE
-
 Rattus norvegicus
IDE
-
 Mus musculus