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Literature summary for 3.4.24.55 extracted from
- Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III (1988), Science, 242, 1415-1418.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not: sulfhydryl-modifying agents | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| periplasm | - |
Escherichia coli | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | contains 1.02-1.14 mol of zinc per mol of enzyme (depending on mutant) | Escherichia coli |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Glucagon + H2O | - |
Escherichia coli | ? | - |
? | |
| Insulin B-chain + H2O | - |
Escherichia coli | ? | - |
? | |
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Release 2023.1 (January 2023)
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