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Literature summary for 3.4.24.54 extracted from

  • Sugihara, H.; Moriura, M.; Nikai, T.
    Purification and properties of a lethal, hemorrhagic protein, Mucrotoxin A, from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus) (1983), Toxicon, 21, 247-255.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
Protobothrops mucrosquamatus
Antivenin
-
Protobothrops mucrosquamatus
EDTA
-
Protobothrops mucrosquamatus
additional information no inhibition by soybean trypsin inhibitor, PCMB, diisopropylfluorophosphate Protobothrops mucrosquamatus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ metalloproteinase, contains 3 mol/mol enzyme Protobothrops mucrosquamatus
Mg2+ metalloproteinase, contains 0.2 mol/mol enzyme Protobothrops mucrosquamatus
Zn2+ metalloproteinase, contains 2 mol/mol enzyme Protobothrops mucrosquamatus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
amino acid composition Protobothrops mucrosquamatus
94000
-
x * 94000, Trimeresurus mucrosquamatus, SDS-PAGE Protobothrops mucrosquamatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Protobothrops mucrosquamatus lethal and hemorrhagic toxin ?
-
?

Organism

Organism UniProt Comment Textmining
Protobothrops mucrosquamatus
-
Chinese habu snake
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information no glycoprotein Protobothrops mucrosquamatus

Purification (Commentary)

Purification (Comment) Organism
from lyophilized crude venom Protobothrops mucrosquamatus

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Protobothrops mucrosquamatus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Protobothrops mucrosquamatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no substrate: casein, exhibits lethal and hemorrhagic activity Protobothrops mucrosquamatus ?
-
?
additional information lethal and hemorrhagic toxin Protobothrops mucrosquamatus ?
-
?

Subunits

Subunits Comment Organism
? x * 94000, Trimeresurus mucrosquamatus, SDS-PAGE Protobothrops mucrosquamatus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Protobothrops mucrosquamatus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
10 min, pH 7, inactivation Protobothrops mucrosquamatus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
pI: 4.3 Protobothrops mucrosquamatus

pH Stability

pH Stability pH Stability Maximum Comment Organism
7
-
10 min, 55°C, inactivation Protobothrops mucrosquamatus