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Literature summary for 3.4.24.42 extracted from

  • Fox, J.W.
    Atrolysin C (2004), Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 671-673.
No PubMed abstract available
Search for more literature for 3.4.24.42

Crystallization (Commentary)

Crystallization (Comment) Organism
X-ray structure of atrolysin C, form D Crotalus atrox

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline inhibits proteolytic and hemorrhagic activity of atrolysin C Crotalus atrox
alpha2-Macroglobulin inhibits proteolytic and hemorrhagic activity of atrolysin C Crotalus atrox
amino acid hydroxymate
-
 Crotalus atrox
chloromethyl ester
-
 Crotalus atrox
EDTA inhibits proteolytic and hemorrhagic activity of atrolysin C Crotalus atrox
additional information inhibitory protein in the serum of Bothrops jararaca Crotalus atrox
phosphoramidon thermolysin inhibitor Crotalus atrox

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ catalytic Crotalus atrox

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
 SDS-PAGE Crotalus atrox

Organism

Organism UniProt Comment Textmining
Crotalus atrox
-
-
-

Purification (Commentary)

Purification (Comment) Organism
gel filtration, ion exchange chromatography Crotalus atrox

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Crotalus atrox
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-Aminobenzoyl-Ala-Gly-Leu-Ala 4-nitrobenzyl amide + H2O
-
 Crotalus atrox ?
-
 ?
bovine aggrecan monomer + H2O purified atrolysin C can cleave at the cleavage sites VIPEN + FFBVG and ITEGE + ARGSV independently Crotalus atrox ?
-
 ?
Dimethylcasein + H2O
-
 Crotalus atrox ?
-
 ?
Fibrinogen + H2O
-
 Crotalus atrox ?
-
 ?
FSFRLT + H2O good substrate Crotalus atrox ?
-
 ?
HTLRKA + H2O good substrate Crotalus atrox ?
-
 ?
IAQLNR + H2O good substrate Crotalus atrox ?
-
 ?
IPLRTV + H2O good substrate Crotalus atrox ?
-
 ?
additional information peptides of four residues or less are not hydrolyzed, no significant degradation of fibrin Crotalus atrox ?
-
 ?
Oxidized insulin B-chain + H2O
-
 Crotalus atrox ?
-
 ?
SFMRLS + H2O good substrate Crotalus atrox ?
-
 ?
TQRKRS + H2O good substrate Crotalus atrox ?
-
 ?

Synonyms

Synonyms Comment Organism
Hemorrhagic toxin c and d
-
 Crotalus atrox