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Literature summary for 3.4.24.35 extracted from

  • Kim, G.W.; Kim, H.J.; Cho, K.J.; Kim, H.W.; Cho, Y.J.; Lee, B.I.
    The role of MMP-9 in integrin-mediated hippocampal cell death after pilocarpine-induced status epilepticus (2009), Neurobiol. Dis., 36, 169-180.
    View publication on PubMed
Search for more literature for 3.4.24.35

Application

Application Comment Organism
medicine MMP-9 is a promising target for a neuroprotective approach to preventing seizure-induced hippocampal damage Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
MMP-9 inhibitor I highly specific inhibition of MMP-9 Mus musculus
Phenanthroline
-
 Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
88000
-
 active form of MMP-9, SDS-PAGE Mus musculus
96000
-
 proMMP-9, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta1-integrin + H2O
-
 Mus musculus ?
-
 ?
Gelatin + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
 Mus musculus
MMP-9
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus MMP-9 expression and activity significantly increase on day 3 after status epilepticus after pilocarpine injection up