Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.35 extracted from

  • Yanti, S.C.; Anggakusuma, S.C.; Gwon, S.H.; Hwang, J.K.
    Kaempferia pandurata Roxb. inhibits Porphyromonas gingivalis supernatant-induced matrix metalloproteinase-9 expression via signal transduction in human oral epidermoid cells (2009), J. Ethnopharmacol., 123, 315-324.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
92000
-
SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
KB cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
Homo sapiens
MMP-9
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the ethanolic extract from Kaempferia pandurata significantly decreases MMP-9 expression at both protein and mRNA levels in a dose-dependent manner(0.002-0.01 mg/ml). Treatment of ethanolic Kaempferia pandurata extract at 0.002, 0.005 and 0.01 mg/ml shows decreases in MMP-9 mRNA levels up to 10%, 13%, and 45%, respectively. Kaempferia pandurata interfers Porphyromonas gingivalis supernatant-induced MMP-9 expression in the oral epidermoid cell line ATCC CCL-17 down
Homo sapiens 10% (v/v) Porphyromonas gingivalis supernatant induces about 2.5fold increased MMP-9 expression in human oral epidermoid cells up