Literature summary for 3.4.24.35 extracted from

Piao, M.S.; Lee, J.K.; Park, C.S.; Ryu, H.S.; Kim, S.H.; Kim, H.S.
Early activation of matrix metalloproteinase-9 is associated with blood-brain barrier disruption after photothrombotic cerebral ischemia in rats (2009), Acta Neurochir. (Wien), 151, 1649-1653.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
matrix metalloproteinase-9	-	Rattus norvegicus
MMP-9	-	Rattus norvegicus

Expression

Organism	Comment	Expression
Rattus norvegicus	MMP-9 protein activity is detected as early as 2 h after the focal ischemic insult (focal cerebral ischemia by photothrombosis), it rapidly increases at 6 h after ischemia, and reaches a maximum level 48 h after the ischemic event. Thereafter, the MMP-9 level abruptly decreases and returns to the baseline at 72 h after the insult	up

General Information

General Information	Comment	Organism
physiological function	MMP-9 is the key factor involved in blood-brain barrier disruption and subsequent brain injury after photothrombotic cerebral ischemia in rats	Rattus norvegicus

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Release 2023.1 (January 2023)