Literature summary for 3.4.24.35 extracted from

Yeh, M.H.; Kao, S.T.; Hung, C.M.; Liu, C.J.; Lee, K.H.; Yeh, C.C.
Hesperidin inhibited acetaldehyde-induced matrix metalloproteinase-9 gene expression in human hepatocellular carcinoma cells (2009), Toxicol. Lett., 184, 204-210.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	MMP-9 expression is increased after a 16 h acetaldehyde treatment (0.1 mM)	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	hesperidin inhibits the secreted and cytosolic MMP-9 forms in HepG2 cells through the inhibition of nuclear factor-kappaB and AP-1	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Hep-G2 cell	-	Homo sapiens	-
hepatoma cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
matrix metalloproteinase-9	-	Homo sapiens
MMP-9	-	Homo sapiens

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Release 2023.1 (January 2023)