Literature summary for 3.4.24.35 extracted from

Hlawaty, H.; Jacob, M.P.; Louedec, L.; Letourneur, D.; Brink, C.; Michel, J.B.; Feldman, L.; Baeck, M.
Leukotriene receptor antagonism and the prevention of extracellular matrix degradation during atherosclerosis and in-stent stenosis (2009), Arterioscler. Thromb. Vasc. Biol., 29, 518-524.

Search for more literature for 3.4.24.35

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	human arteries subjected to ex vivo angioplasty and stent implantation display increased in-stent intimal hyperplasia and higher MMP-9 activity in the presence of leukotriene B4	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
BIIL284	BIIL284 treatment (3 mg/kg once daily for 2 weeks) significantly reduces the extracellular matrix metalloproteinase-9 activity in stented arteries	Oryctolagus cuniculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
soluble	-	Homo sapiens	-	-
soluble	-	Oryctolagus cuniculus	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Oryctolagus cuniculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
artery	-	Homo sapiens	-
artery	-	Oryctolagus cuniculus	-
Rb-1 cell	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Gelatin + H2O	-	Homo sapiens	?	-	?
Gelatin + H2O	-	Oryctolagus cuniculus	?	-	?

Synonyms

Synonyms	Comment	Organism
matrix metalloproteinase-9	-	Homo sapiens
matrix metalloproteinase-9	-	Oryctolagus cuniculus
MMP-9	-	Homo sapiens
MMP-9	-	Oryctolagus cuniculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)