Any feedback?
Literature summary for 3.4.24.29 extracted from
- Role of metalloprotease in activation of the precursor of staphylococcal protease (1978), J. Bacteriol., 136, 607-613.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Staphylococcus aureus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | reactivates 1,10-phenanthroline inactivated enzyme with 160% of the activity of the native enzyme | Staphylococcus aureus | |
| Zn2+ | reactivates 1,10-phenanthroline inactivated enzyme | Staphylococcus aureus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 38000 | - |
x * 38000, Staphylococcus aureus, SDS-PAGE | Staphylococcus aureus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Staphylococcus aureus | activates the precursor of another protease secreted by the same organism, staphylococcal protease | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus aureus | - |
mutant of strain V8 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Staphylococcus aureus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Staphylococcus aureus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | specificity for peptide bonds on the N-terminal side of large hydrophobic residues | Staphylococcus aureus | ? | - |
? | |
| additional information | activates the precursor of another protease secreted by the same organism, staphylococcal protease | Staphylococcus aureus | ? | - |
? | |
| Nalpha-Furylacryloyl-Gly-Leu amide + H2O | - |
Staphylococcus aureus | ? | - |
? | |
| Oxidized insulin B-chain + H2O | cleaves at His5-Leu6, His10-Leu11, Ala14-Leu15, Tyr16-Leu17, Gly23-Phe24, Phe25-Tyr26 | Staphylococcus aureus | Hydrolyzed oxidized insulin | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 38000, Staphylococcus aureus, SDS-PAGE | Staphylococcus aureus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
N-alpha-furylacryloyl-Gly-Leu amide | Staphylococcus aureus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
