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Literature summary for 3.4.24.26 extracted from

  • Kida, Y.; Higashimoto, Y.; Inoue, H.; Shimizu, T.; Kuwano, K.
    A novel secreted protease from Pseudomonas aeruginosa activates NF-kappaB through protease-activated receptors (2008), Cell. Microbiol., 10, 1491-1504.
    View publication on PubMed
Search for more literature for 3.4.24.26

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Pseudomonas aeruginosa
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 x * 100000, SDS-PAGE Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information large exopeptidase LepA activates nuclear factor kappa-kB-driven promoter through human protease activated receptors PAR-1, -2 or -4 and cleaves the peptides corresponding to the tethered ligand region of human PAR-1, -2 and -4 at a specific site with exposure of their tethered ligands Pseudomonas aeruginosa ?
-
 ?
PAR-1 peptide + H2O cleavage at the R41-S42 site Pseudomonas aeruginosa ?
-
 ?
PAR-2 peptide + H2O cleavage at the R36-S37 site Pseudomonas aeruginosa ?
-
 ?
PAR-4 peptide + H2O cleavage at the R47-G48 site Pseudomonas aeruginosa ?
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE Pseudomonas aeruginosa

Synonyms

Synonyms Comment Organism
LepA
-
 Pseudomonas aeruginosa