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Literature summary for 3.4.24.26 extracted from

  • Padrines, M.; Bieth, J.G.
    Oxidized and Met358-->Leu mutated alpha 1-proteinase inhibitor as substrates of Pseudomonas aeruginosa elastase (1993), Biochim. Biophys. Acta, 1163, 61-66.
    View publication on PubMed
Search for more literature for 3.4.24.26

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa P14756
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoyl-Ala-Gly-Leu-Ala-4-nitrobenzylamide + H2O 25°C, pH 7.4 Pseudomonas aeruginosa ?
-
 ?
alpha1-proteinase inhibitor + H2O 25°C, pH 7.4, cleavage occurs at the Pro357-Met358 bond (wild-type and recombinant Met358 inhibitor) and at the Pro357-Leu358 bond (recombinant mutant M358L inhibitor) Pseudomonas aeruginosa ?
-
 ?
N-chlorosuccinimide-oxidized inhibitor + H2O 25°C, pH 7.4, cleavage occurs between Glu354 and Ala355 Pseudomonas aeruginosa ?
-
 ?

Synonyms

Synonyms Comment Organism
PsE
-
 Pseudomonas aeruginosa
Pseudomonas aeruginosa elastase
-
 Pseudomonas aeruginosa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.8
-
 with 2-aminobenzoyl-Ala-Gly-Leu-Ala-4-nitrobenzylamide as substrate Pseudomonas aeruginosa
6
-
 with the native alpha1-proteinase inhibitor as substrate Pseudomonas aeruginosa
6.5
-
 with the recombinant mutant M358L inhibitor as substrate Pseudomonas aeruginosa
7
-
 with N-chlorosuccinimide-oxidized inhibitor as substrate Pseudomonas aeruginosa