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Literature summary for 3.4.24.24 extracted from

  • Gonzalez-Cuevas, J.; Bueno-Topete, M.; Armendariz-Borunda, J.
    Urokinase plasminogen activator stimulates function of active forms of stromelysin and gelatinases (MMP-2 and MMP-9) in cirrhotic tissue (2006), J. Gastroenterol. Hepatol., 21, 1544-1554.
    View publication on PubMed

Application

Application Comment Organism
medicine endogenous urokinase plasminogen activator from cultured hepatic stellate cells significantly induces the active forms of enzyme and matrix metalloproteinase MMP-9 in cirrhotic tissue slices. Transfection of hepatic stellate cells with urokinase plasminogen activator gene results in overactivation of enzyme and matrix metalloproteinases MMP-3 and MMP-9 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
liver cirrhotic liver Rattus norvegicus
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