Literature summary for 3.4.24.24 extracted from

Gehrmann, M.L.; Douglas, J.T.; Banyai, L.; Tordai, H.; Patthy, L.; Llinas, M.
Modular autonomy, ligand specificity, and functional cooperativity of the three in-tandem fibronectin type II repeats from human matrix metalloproteinase 2 (2004), J. Biol. Chem., 279, 46921-46929.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	investigation of ligand binding properties of the three fibronectin type II repeats of enzyme using collagen mimic peptide (L-Pro-L-Pro-Gly)6 and propeptide segment PIIKFPGDVA. Each module interacts essentially as an autonomous unit with these peptides, but enzyme shows cooperative participation toward a closer mimic of collagen, ((Gly-L-Pro-L-Pro-)12)3 in triple helical configuration	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)