Literature summary for 3.4.24.24 extracted from

Kozaci, L.D.; Guner, A.; Oktay, G.; Guner, G.
Alterations in biochemical components of extracellular matrix in intervertebral disc herniation: role of MMP-2 and TIMP-2 in type II collagen loss (2006), Cell Biochem. Funct., 24, 431-436.

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Application

Application	Comment	Organism
additional information	in patients with degenerative disc disease, proenzyme levels in nucleus pulposus of intervertebral disc are higher at early stages of the disease. Proenzyme and tissue inhibitor of metalloproteinase-2 levels negatively correlate in herniated disc samples, and proenzyme levels negatively correlate with the collagen content	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with degenerative disc disease	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
disc	nucleus pulposus of intervertebral disc	Homo sapiens	-

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Release 2023.1 (January 2023)