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BRENDA support

Literature summary for 3.4.24.23 extracted from

  • Chen, P.; Abacherli, L.E.; Nadler, S.T.; Wang, Y.; Li, Q.; Parks, W.C.
    MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha2beta1 integrin activation (2009), PLoS ONE, 4, e6565.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelium
-
Mus musculus
-
lung
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Mus musculus
-

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase-7
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Mus musculus
MMP7
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Mus musculus

Expression

Organism Comment Expression
Mus musculus lung injury promotes the expression of matrix metalloproteinase-7 up

General Information

General Information Comment Organism
physiological function MMP7 is required for cell migration. Lung injury promotes the expression of matrix metalloproteinase-7, which is required for neutrophil recruitment and re-epithelialization. MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha2beta1 integrin activation. MMP7 releases syndecan-1 restrictions on wound closure, overview Mus musculus