Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor, it upregulates ErbB4 receptor expression, mediates ErbB4 localization in cytoplasm and nucleus, solubilizes the ErbB4 receptor cognate ligand heaprin-bound epidermal growth factor, and mediates the proteolytic processing of ErbB4, overview, MMP-7 shows in vitro and in vivo proliferative activity | ? | - |
? | |
additional information | Mus musculus | matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor, it upregulates ErbB4 receptor expression, mediates ErbB4 localization in cytoplasm and nucleus, solubilizes the ErbB4 receptor cognate ligand heaprin-bound epidermal growth factor, and mediates the proteolytic processing of ErbB4, overview, MMP-7 shows in vitro and in vivo proliferative activity | ? | - |
? | |
additional information | Mus musculus C57BL/6 | matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor, it upregulates ErbB4 receptor expression, mediates ErbB4 localization in cytoplasm and nucleus, solubilizes the ErbB4 receptor cognate ligand heaprin-bound epidermal growth factor, and mediates the proteolytic processing of ErbB4, overview, MMP-7 shows in vitro and in vivo proliferative activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09237 | - |
- |
Mus musculus | Q10738 | C57BL/6 mice | - |
Mus musculus C57BL/6 | Q10738 | C57BL/6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | early stage primary cancers, MMP-7 correlates with breast cancer development, overexpression of MMP-7 and ErbB4, overview | Homo sapiens | - |
c57MG cell | mammary gland epithelial cell line | Mus musculus | - |
epithelium | - |
Mus musculus | - |
mammary gland | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor, it upregulates ErbB4 receptor expression, mediates ErbB4 localization in cytoplasm and nucleus, solubilizes the ErbB4 receptor cognate ligand heaprin-bound epidermal growth factor, and mediates the proteolytic processing of ErbB4, overview, MMP-7 shows in vitro and in vivo proliferative activity | Homo sapiens | ? | - |
? | |
additional information | matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor, it upregulates ErbB4 receptor expression, mediates ErbB4 localization in cytoplasm and nucleus, solubilizes the ErbB4 receptor cognate ligand heaprin-bound epidermal growth factor, and mediates the proteolytic processing of ErbB4, overview, MMP-7 shows in vitro and in vivo proliferative activity | Mus musculus | ? | - |
? | |
additional information | matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor, it upregulates ErbB4 receptor expression, mediates ErbB4 localization in cytoplasm and nucleus, solubilizes the ErbB4 receptor cognate ligand heaprin-bound epidermal growth factor, and mediates the proteolytic processing of ErbB4, overview, MMP-7 shows in vitro and in vivo proliferative activity | Mus musculus C57BL/6 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase 7 | - |
Homo sapiens |
Matrix metalloproteinase 7 | - |
Mus musculus |
MMP-7 | - |
Homo sapiens |
MMP-7 | - |
Mus musculus |