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Literature summary for 3.4.24.23 extracted from
- Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7) (2000), J. Biol. Chem., 275, 4183-4191.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| heparin | enhances activity 15fold | Rattus norvegicus |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| active MMP-7 lacking the propeptide expressed in Escherichia coli BL21(DE3) | Homo sapiens |
| recombinant proMMP-7 expressed in Escherichia coli BL21(DE3) | Rattus norvegicus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E198Q | site-directed mutagenesis | Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 25000 | - |
activated form, Western blotting | Rattus norvegicus |
| 28000 | - |
proform, Western blotting | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
| Rattus norvegicus | - |
rat, Sprague-Dawley | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant enzyme | Homo sapiens |
| recombinant enzyme | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| bovine carboxymethylated-transferrin + H2O | - |
Rattus norvegicus | ? | - |
? | |
| pig gelatin type A + H2O | - |
Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Matrix metalloproteinase 7 | - |
Homo sapiens |
| Matrix metalloproteinase 7 | - |
Rattus norvegicus |
| MMP-7 | - |
Homo sapiens |
| MMP-7 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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