Inhibitors | Comment | Organism | Structure |
---|---|---|---|
carboxylate | - |
Mammalia |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mammalia | apart from its activity against extracellular matrix, the enzyme provides a mechanism for the regulation of leukocyte elastase activity through its capacity to degrade alpha1-antitrypsin | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mammalia | - |
expressed in NSO mouse myeloma cells | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha1-antitrypsin + H2O | a single cleavage at the Phe352-Leu353 peptide bond, a locus within active-site loop produces 2 fragments of approximately 50000 MW and 4000 MW | Mammalia | ? | - |
? | |
additional information | apart from its activity against extracellular matrix, the enzyme provides a mechanism for the regulation of leukocyte elastase activity through its capacity to degrade alpha1-antitrypsin | Mammalia | ? | - |
? |