Literature summary for 3.4.24.22 extracted from

Lorente, L.; Martin, M.M.; Labarta, L.; Diaz, C.; Sole-Violan, J.; Blanquer, J.; Orbe, J.; Rodriguez, J.A.; Jimenez, A.; Borreguero-Leon, J.M.; Belmonte, F.; Medina, J.C.; Lliminana, M.C.; Ferrer-Agueero, J.M.; Ferreres, J.; Mora, M.L.; Lubillo, S.; Sanchez, M.; Barrios, Y.; Sierra, A.; Paramo, J.A.
Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis (2009), Crit. Care, 13, R158.

Inhibitors

Inhibitors	Comment	Organism	Structure
TIMP-1	increased levels in severe sepsis	Homo sapiens

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Homo sapiens	-	-
extracellular matrix	-	Homo sapiens	31012	-

Metals/Ions	Comment	Organism	Structure
Zn2+	MMP-10 is a zinc-containing endoproteinase	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining
serum	increased MMP-10 levels in severe sepsis	Homo sapiens	-

Synonyms	Comment	Organism
Matrix metalloproteinase-10	-	Homo sapiens
MMP-10	-	Homo sapiens

Organism	Comment	Expression
Homo sapiens	increased MMP-10 levels in severe sepsis	up

General Information	Comment	Organism
malfunction	association between MMP-9, MMP-10, TIMP-1, and MMP-9/TIMP-1 ratios and parameters of sepsis severity, overview	Homo sapiens
additional information	interleukin-10 positively correlates with inhibitor TIMP-1 and MMP-10 in sepsis patients	Homo sapiens
physiological function	matrix metalloproteinases play a role in infectious diseases through extracellular matrix degradation, which favors the migration of immune cells from the bloodstream to sites of inflammation	Homo sapiens