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Literature summary for 3.4.24.19 extracted from

  • Garrigue-Antar, L.; Barker, C.; Kadler, K.E.
    Identification of amino acid residues in bone morphogenetic protein-1 important for procollagen C-proteinase activity (2001), J. Biol. Chem., 276, 26237-26242.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
recombinant wild-type and mutant BMP-1 expressed in COS-7 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
C63G site-directed mutagenesis Homo sapiens
C65A site-directed mutagenesis Homo sapiens
C66G site-directed mutagenesis Homo sapiens
C85A site-directed mutagenesis Homo sapiens
E94A site-directed mutagenesis Homo sapiens
K176A site-directed mutagenesis Homo sapiens
K87A site-directed mutagenesis Homo sapiens
K87A/K176A site-directed mutagenesis Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc metalloproteinase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen C-propeptide + H2O Homo sapiens cleaves the C-propeptides of type I procollagen during the synthesis of extracellular matrix collagen fibrils ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P13497 human
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
procollagen C-propeptide + H2O cleaves the C-propeptides of type I procollagen during the synthesis of extracellular matrix collagen fibrils Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
BMP-1
-
Homo sapiens
bone morphogenetic protein-1
-
Homo sapiens
PCP
-
Homo sapiens
Procollagen C-proteinase
-
Homo sapiens