Inhibitors | Comment | Organism | Structure |
---|---|---|---|
actinonin | - |
Homo sapiens | |
batimastat | - |
Homo sapiens | |
captopril | - |
Homo sapiens | |
galardin | - |
Homo sapiens | |
L-Pro-L-Leu-Gly-hydroxamate | - |
Homo sapiens | |
N-isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid | - |
Homo sapiens | |
Ro 32-7315 | - |
Homo sapiens | |
TAPI-0 | i.e. tumour necrosis factor alpha protease inhibitor-0 | Homo sapiens | |
TAPI-2 | i.e. tumour necrosis factor alpha protease inhibitor-2 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen IV + H2O | - |
Homo sapiens | ? | - |
? | |
Fibronectin + H2O | cleavage at positions Y294-Q295, N709-T210 and in the linker regions between fibronectin type I repeats 5 and 6 and fibronectin type II repeats 1 and 2 | Homo sapiens | ? | - |
? | |
additional information | no substrate: intact collagen I | Homo sapiens | ? | - |
? | |
nidogen-1 + H2O | cleavage at D67-R68 and Q363-H364 | Homo sapiens | ? | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00002 | - |
actinonin | pH 7.5, 37°C | Homo sapiens | |
0.00017 | - |
galardin | pH 7.5, 37°C | Homo sapiens | |
0.0004 | - |
N-isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid | pH 7.5, 37°C | Homo sapiens | |
0.00053 | - |
L-Pro-L-Leu-Gly-hydroxamate | pH 7.5, 37°C | Homo sapiens | |
0.0015 | - |
TAPI-2 | pH 7.5, 37°C | Homo sapiens | |
0.0016 | - |
Ro 32-7315 | pH 7.5, 37°C | Homo sapiens | |
0.0022 | - |
TAPI-0 | pH 7.5, 37°C | Homo sapiens | |
0.0044 | - |
batimastat | pH 7.5, 37°C | Homo sapiens | |
0.074 | - |
captopril | pH 7.5, 37°C | Homo sapiens |