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Literature summary for 3.4.24.17 extracted from

  • Lee, E.J.; Kim, S.Y.; Hyun, J.W.; Min, S.W.; Kim, D.H.; Kim, H.S.
    Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression (2010), Chem. Biol. Interact., 185, 18-24.
    View publication on PubMed
Search for more literature for 3.4.24.17

Cloned(Commentary)

Cloned (Comment) Organism
NF-kappaB and AP-1 are important transcription factors for MMP-3 gene expression. Glycitein inhibits the promoter activitiy of MMP-3, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astroglioma cell
-
 Homo sapiens
-
glioma cell
-
 Homo sapiens
-
U-87MG cell astroglioma cells Homo sapiens
-

Synonyms

Synonyms Comment Organism
MMP-3
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens glycitein, i.e. 4',7-dihydroxy-6-methoxyisoflavone, a bacterial metabolite of the isoflavone glycitin, downregulates MMP-3 gene expression by inhibiting the promoter activity of MMP-3 down

General Information

General Information Comment Organism
malfunction MMP-3 is involved in glioma cell invasion, overview Homo sapiens
metabolism NF-kappaB and AP-1 are important transcription factors for MMP-3 gene expression. Glycitein, a bacterial metabolite of the isoflavone glycitin, inhibits glioma cell invasion through downregulation of MMP-3 and MMP-9 gene expression, overview Homo sapiens