Literature summary for 3.4.24.17 extracted from

Van Themsche, C.; Potworowski, E.F.; St-Pierre, Y.
Stromelysin-1 (MMP-3) is inducible in T lymphoma cells and accelerates the growth of lymphoid tumors in vivo (2004), Biochem. Biophys. Res. Commun., 315, 884-891.

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Application

Application	Comment	Organism
medicine	enzyme overexpression im lymphoma transfectants significantly improves their ability to migrate through the matrix. Animals injected with lymphoma cells expressing enzyme constitutively develop thymic lymphoma more rapidly than those injected with control cells. Local expression of enzyme promotes lymphoma progression	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	enzyme overexpression im lymphoma transfectants significantly improves their ability to migrate through the matrix. Animals injected with lymphoma cells expressing enzyme constitutively develop thymic lymphoma more rapidly than those injected with control cells. Local expression of enzyme promotes lymphoma progression	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymphoma cell	enzyme expression in transiently induced during specific intercellular contact with endothelial cells. Enzyme expression is tightly regulated upon lymphoma cell/stromal cell interaction	Mus musculus	-

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Release 2023.1 (January 2023)