Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.16 extracted from

  • Millican, P.E.; Kenny, A.J.; Turner, A.J.
    Purification and properties of a neurotensin-degrading endopeptidase from pig brain (1991), Biochem. J., 276, 583-591.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Sus scrofa 5829
-
membrane
-
Sus scrofa 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
x * 75000, SDS-PAGE Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification glycoprotein Sus scrofa

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.298
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg-Arg-Pro-Tyr-Ile-Leu + H2O i.e. neurotensin(8-13) Sus scrofa Arg-Arg-Pro + Tyr-Ile-Leu
-
?
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O cleavage sites: Pro4-Gly5, Glyn5-Glyn6, and Phe8-Gly9 Sus scrofa Arg-Pro-Lys-Pro-Gln + Gln-Phe-Phe-Gly-Leu-Met-NH2 + Arg-Pro-Lys-Pro-Gln-Gln + Phe-Phe-Gly-Leu-Met-NH2 + Arg-Pro-Lys-Pro
-
?
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O
-
Sus scrofa Arg-Pro-Pro-Gly-Phe + Ser-Pro-Phe-Arg
-
?
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe + H2O i.e. angiotensin II Sus scrofa Asp-Arg-Val-Tyr + Ile-His-Pro-Phe
-
?
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O i.e. angiotensin I, cleavage site: Pro7-Phe8 Sus scrofa Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
?
benzoyl-Gly-Ala-Ala-Phe-4-aminobenzoate + H2O
-
Sus scrofa benzoyl-Gly + Ala-Ala-Phe-4-aminobenzoate
-
?
Luteinizing hormone-releasing hormone + H2O
-
Sus scrofa ?
-
?
Lys-Ile-Pro-Tyr-Ile-Leu + H2O i.e. neuromedin Sus scrofa Lys-Ile-Pro + Tyr-Ile-Leu
-
?
pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr + H2O i.e. neurotensin(1-11) Sus scrofa pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg + Arg-Pro-Tyr
-
?
pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O cleavage sites: Arg8-Arg9 and Pro10-Tyr11 Sus scrofa pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
?
t-butyloxycarbonyl-Phe-Ala-Ala-Phe-4-aminobenzoate + H2O
-
Sus scrofa t-butyloxycarbonyl-Phe + Ala-Ala-Phe-4-aminobenzoate
-
?
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O
-
Sus scrofa Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
?
Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro-Lys + H2O i.e. alpha-neoendorphin Sus scrofa Tyr-Gly-Gly-Phe-Leu-Arg-Lys + Tyr-Pro-Lys
-
?

Subunits

Subunits Comment Organism
? x * 75000, SDS-PAGE Sus scrofa