Protein Variants | Comment | Organism |
---|---|---|
additional information | Blastx analysis shows that the igaB gene is homologous to the IgA1 protease genes of Neisseria gonorrhoeae and Neisseria meningitidis. The degree of homology of igaB to neisserial iga genes is greater than the homology of igaB to Haemophilus iga genes | Haemophilus influenzae |
additional information | mutants that are deficient in iga, igaB, and both genes are constructed in Haemophilus influenzae strain 11P6H. Analysis of these mutants indicates that igaB is the primary mediator of IgA1 protease activity in this strain | Haemophilus influenzae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemophilus influenzae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | reverse transcriptase PCR shows that igB is transcribed in Haemophilus influenza | Haemophilus influenzae | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
IgA1 protease activity assays on 20 clinical isolates indicates that the igaB gene is associated with increased levels of IgA1 protease activity | Haemophilus influenzae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Immunoglobulin A1 + H2O | - |
Haemophilus influenzae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IgA1 protease | - |
Haemophilus influenzae |
igaB | - |
Haemophilus influenzae |
igaB | represents a second immunoglobulin A1 protease gene in nontypeable Haemophilus influenza | Haemophilus influenzae |