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Literature summary for 3.4.23.B5 extracted from

  • Eizert, H.; Bander, P.; Bagossi, P.; Sperka, T.; Miklossy, G.; Boross, P.; Weber, I.T.; Toezser, J.
    Amino acid preferences of retroviral proteases for amino-terminal positions in a type 1 cleavage site (2008), J. Virol., 82, 10111-10117.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Moloney murine leukemia virus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
VDQNYPIVQ + H2O medium-sized polar residues (Ser, Thr, and Asp) are preferred at position P4 Moloney murine leukemia virus VDQNY + PIVQ
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VSQNAPIVQ + H2O Phe, Tyr, Leu or Met, Ala in order of decreasing efficiency, at position P1 Moloney murine leukemia virus VSQNA + PIVQ
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VSQNFPIVQ + H2O Phe, Tyr, Leu or Met, Ala in order of decreasing efficiency, at position P1 Moloney murine leukemia virus VSQNF + PIVQ
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VSQNLPIVQ + H2O Phe, Tyr, Leu or Met, Ala in order of decreasing efficiency, at position P1 Moloney murine leukemia virus VSQNL + PIVQ
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VSQNMPIVQ + H2O Phe, Tyr, Leu or Met, Ala in order of decreasing efficiency, at position P1 Moloney murine leukemia virus VSQNM + PIVQ
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VSQNYPIVQ + H2O medium-sized polar residues (Ser, Thr, and Asp) are preferred at position P4 Moloney murine leukemia virus VSQNY + PIVQ
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VSQNYPIVQ + H2O Phe, Tyr, Leu or Met, Ala in order of decreasing efficiency, at position P1 Moloney murine leukemia virus VSQNY + PIVQ
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VTQNYPIVQ + H2O medium-sized polar residues (Ser, Thr, and Asp) are preferred at position P4 Moloney murine leukemia virus VTQNY + PIVQ
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