Literature summary for 3.4.23.B4 extracted from

Lee, T.; Laco, G.S.; Torbett, B.E.; Fox, H.S.; Lerner, D.L.; Elder, J.H.; Wong, C.H.
Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo (1998), Proc. Natl. Acad. Sci. USA, 95, 939-944.

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Cloned(Commentary)

Cloned (Comment)	Organism
mutant enzmyes V59I, Q99V and G5I/N55T/C84K, expression in Escherichia coli BL21 cells	feline immunodeficiency virus

Protein Variants

Protein Variants	Comment	Organism
G5I/N55T/C84K	autoproteolysis-resistant mutant, no significant change in Km or turnover number values between the mutant enzyme and the wild-type enzyme	feline immunodeficiency virus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
10790	-	matrix-assisted laser desorption ionization analysis	feline immunodeficiency virus

Organism

Organism	UniProt	Comment	Textmining
feline immunodeficiency virus	-	-	-

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Release 2023.1 (January 2023)