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Literature summary for 3.4.23.B13 extracted from

  • Sedlacek, J.; Fabry, M.; Coward, J.E.; Horejsi, M.; Strop, P.; Luftig, R.B.
    Myeloblastosis associated virus (MAV) proteinase site-mutated to be HIV-like has a higher activity and allows production of infectious but morphologically altered virus (1993), Virology, 192, 667-672.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
mutant enzyme A100L/V104T/R105P/G106V/S107N Avian myeloblastosis-associated virus

Protein Variants

Protein Variants Comment Organism
A100L/V104T/R105P/G106V/S107N mutant enzyme shows increased proteolytic activity in vitro, mutant plasmid-transfected turkey fibroblasts display an unimpaired virus production in cell cultures. The mutant progeny virus is infectious and ist pattern of gag processing products appears identical to that of wild-type virus. The predominant morphology of mutant viral particles is altered Avian myeloblastosis-associated virus

Organism

Organism UniProt Comment Textmining
Avian myeloblastosis-associated virus
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