Literature summary for 3.4.23.B11 extracted from

Enssle, J.; Fischer, N.; Moebes, A.; Mauer, B.; Smola, U.; Rethwilm, A.
Carboxy-terminal cleavage of the human foamy virus Gag precursor molecule is an essential step in the viral life cycle (1997), J. Virol., 71, 7312-7317.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
pr74 + H2O	Human spumaretrovirus	Pr74 is the gag precursor protein with a molecular mass of 74000 Da from which a 70000 Da protein, p70, is cleaved by the viral protease. Carboxy-terminal cleavage of the human foamy virus Gag precursor molecule is an essential step in the viral life cycle, absolute requirement for viral infectivity	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Human spumaretrovirus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
pr74 + H2O	Pr74 is the gag precursor protein with a molecular mass of 74000 Da from which a 70000 Da protein, p70, is cleaved by the viral protease. Carboxy-terminal cleavage of the human foamy virus Gag precursor molecule is an essential step in the viral life cycle, absolute requirement for viral infectivity	Human spumaretrovirus	?	-	?

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Release 2023.1 (January 2023)