Cloned (Comment) | Organism |
---|---|
expressed in HEK-293 cells | Lethenteron camtschaticum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Lethenteron camtschaticum | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
42772 | - |
x * 42772, calculated from amino acid sequence | Lethenteron camtschaticum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lethenteron camtschaticum | A0A0A7HF39 | Japanese lamprey | - |
Purification (Comment) | Organism |
---|---|
ANTI-FLAG M2 affinity resin column chromatography, and gel filtration | Lethenteron camtschaticum |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
buccal gland | highest expression | Lethenteron camtschaticum | - |
gill | - |
Lethenteron camtschaticum | - |
heart | - |
Lethenteron camtschaticum | - |
immune system | - |
Lethenteron camtschaticum | - |
intestine | - |
Lethenteron camtschaticum | - |
kidney | - |
Lethenteron camtschaticum | - |
liver | - |
Lethenteron camtschaticum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fibrinogen + H2O | the Aalpha and Bbeta chains of fibrinogen are digested completely, and the gamma chain is degraded partly | Lethenteron camtschaticum | ? | - |
? | |
Hemoglobin + H2O | - |
Lethenteron camtschaticum | ? | - |
? | |
serum albumin + H2O | - |
Lethenteron camtschaticum | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 42772, calculated from amino acid sequence | Lethenteron camtschaticum |
Synonyms | Comment | Organism |
---|---|---|
CatD | - |
Lethenteron camtschaticum |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Lethenteron camtschaticum | calculated from amino acid sequence | - |
6.2 |
Organism | Comment | Expression |
---|---|---|
Lethenteron camtschaticum | cathepsin D expression in the buccal gland is increased 6.5-8.5fold after challenge with Escherichia coli or Staphylococcus aureus | up |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin D plays key roles in immune response to exogenous pathogens and also acts as a digestive enzyme during the adaptation to a blood-feeding lifestyle | Lethenteron camtschaticum |