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Literature summary for 3.4.23.5 extracted from

  • Minarowska, A.; Minarowski, L.; Karwowska, A.; Sands, D.; Dabrowska, E.
    The activity of cathepsin D in saliva of cystic fibrosis patients (2007), Folia Histochem. Cytobiol., 45, 165-168.
    View publication on PubMed
Search for more literature for 3.4.23.5

Application

Application Comment Organism
medicine the activity of cathepsin D in saliva of cystic fibrosis patients is significantly higher than in healthy controls before the stimulation of excretion with paraffin pledgets Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
saliva
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 the activity of CTSD in controls is 45.9 Tyr nmol/mL/4h before stimulation and 109.3 Tyr nmol/mL/4h after stimulation of excretion with paraffin pledgets. In cystic fibrosis group CTSD activity before stimulation is 134.5 Tyr nmol/mL/4h and after stimulation 134.4 Tyr nmol/mL/4h Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Acid-denatured hemoglobin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
cathepsin D
-
 Homo sapiens
CTSD
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5
-
 assay at Homo sapiens