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Literature summary for 3.4.23.5 extracted from

  • Pimenta, D.C.; Chen, V.C.; Chao, J.; Juliano, M.A.; Juliano, L.
    alpha1-antichymotrypsin and kallistatin hydrolysis by human cathepsin D (2000), J. Protein Chem., 19, 411-418.
    View publication on PubMed
Search for more literature for 3.4.23.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00008
-
 2-aminobenzoyl-AIKFFSAQTNRHILRFNR-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.00016
-
 2-aminobenzoyl-KITLLSALVETRIVRFNRQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.00037
-
 2-aminobenzoyl-AIKFFSA-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.00046
-
 2-aminobenzoyl-AIKFFSAQ-N-(2,4-dinitrophenyl)ethylenediamine 37°C, pH 4.0 Homo sapiens
0.00051
-
 2-aminobenzoyl-KITLLSAQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.00074
-
 2-aminobenzoyl-KITLLSALVETRQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.0008
-
 2-aminobenzoyl-AIKFFSAQTNR-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.00094
-
 2-aminobenzoyl-KITLLSAQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 commercial preparation
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoyl-AIKFFSA-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Homo sapiens 2-aminobenzoyl-AIKF + FSA-(N-(2,4-dinitrophenyl)ethylenediamine)
-
 ?
2-aminobenzoyl-AIKFFSAQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O peptide derived from kallistatin Homo sapiens 2-aminobenzoyl-AIKF + FSAQ-N-(2,4-dinitrophenyl)ethylenediamine
-
 ?
2-aminobenzoyl-AIKFFSAQTNR-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Homo sapiens 2-aminobenzoyl-AIKF + FSAQTNR-(N-(2,4-dinitrophenyl)ethylenediamine)
-
 ?
2-aminobenzoyl-AIKFFSAQTNRHILRFNR-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Homo sapiens 2-aminobenzoyl-AIKF + FSAQTNRHILRFNR-(N-(2,4-dinitrophenyl)ethylenediamine)
-
 ?
2-aminobenzoyl-AIKFFSAQTNRHILRFNRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O peptide derived from kallistatin Homo sapiens 2-aminobenzoyl-AIKF + FSAQTNRHILRFNRQ-N-(2,4-dinitrophenyl)ethylenediamine
-
 ?
2-aminobenzoyl-AIKFFSAQTNRQ-N-(2,4-dinitrophenyl)ethylenediamine + H2O peptide derived from kallistatin Homo sapiens 2-aminobenzoyl-AIKF + FSAQTNRQ-N-(2,4-dinitrophenyl)ethylenediamine
-
 ?
2-aminobenzoyl-KITLLSALVETRIVRFNRQ-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Homo sapiens ?
-
 ?
2-aminobenzoyl-KITLLSALVETRQ-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Homo sapiens ?
-
 ?
2-aminobenzoyl-KITLLSAQ-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Homo sapiens ?
-
 ?
alpha1-Antichymotrypsin + H2O cleavage between L383S384 and between A385V386 Homo sapiens ?
-
 ?
kallistatin + H2O cleavage between F387F388, between F388S389, between L404V405 Homo sapiens ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 2-aminobenzoyl-AIKFFSAQ-N-(2,4-dinitrophenyl)ethylenediamine 37°C, pH 4.0 Homo sapiens
0.17
-
 2-aminobenzoyl-KITLLSALVETRIVRFNRQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
0.99
-
 2-aminobenzoyl-AIKFFSAQTNRHILRFNR-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
2.3
-
 2-aminobenzoyl-KITLLSAQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
2.44
-
 2-aminobenzoyl-AIKFFSAQTNRHILRFNR-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
2.8
-
 2-aminobenzoyl-KITLLSALVETRQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
2.94
-
 2-aminobenzoyl-AIKFFSAQTNRHILRFNR-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
3.13
-
 2-aminobenzoyl-AIKFFSA-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
3.6
-
 2-aminobenzoyl-KITLLSAQ-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
4.16
-
 2-aminobenzoyl-AIKFFSA-(N-(2,4-dinitrophenyl)ethylenediamine) 37°C, pH 4.0 Homo sapiens
6.34
-
 2-aminobenzoyl-AIKFFSAQ-N-(2,4-dinitrophenyl)ethylenediamine 37°C, pH 4.0 Homo sapiens