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Literature summary for 3.4.23.5 extracted from
- Cathepsin D is specifically inhibited by deoxyribonucleic acids (2002), FEBS Lett., 517, 281-284.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| DNA18b | i.e. 5-ggctcaggtacccagaga-3, at 100 nM, 40% inhibition | Bos taurus | |
| DNA53b | i.e. 5-gctctagatcaatgatgatgatgatgatgctggcgtttccgaggggggcgctt-3, 80% inhibition at 100 nM, complete inhibition at 0.001 mM | Bos taurus | |
| additional information | inhibitory activity of DNA is significantly dependent on Tm values of each nucleotide | Bos taurus | |
| plasmid DNA | length 50 kbp, double strand, 50% inhibition at 60 pM | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
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Release 2023.1 (January 2023)
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