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Literature summary for 3.4.23.5 extracted from
- Purification and properties of cathepsin D from porcine spleen (1976), J. Biol. Chem., 251, 4528-4536.
General Stability
| General Stability | Organism |
|---|---|
| stable upon freezing | Sus scrofa |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,2-epoxy-3-(4-nitrophenoxy)propane | - |
Sus scrofa |  |
| Diazoacetyl-DL-norleucine methyl ester | - |
Sus scrofa | |
| ethanol | 5% | Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
pig | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| spleen | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Hemoglobin + H2O | - |
Sus scrofa | ? | - |
? | |
| insulin + H2O | oxidized A chain and B chain | Sus scrofa | ? | - |
? | |
| peptide D + H2O | - |
Sus scrofa | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 34000-35000, SDS-PAGE | Sus scrofa |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
stable up to | Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 2.9 | - |
0.1 M sodium acetate or formate buffer, hydrolysis of hemoglobin | Sus scrofa |
| 3.4 | - |
2 pH-optima: at pH 3.4 and at pH 3.8, 0.5 M sodium acetate or formate buffer, hydrolysis of hemoglobin | Sus scrofa |
| 3.8 | - |
2 pH-optima: at pH 3.4 and at pH 3.8, 0.5 M sodium acetate or formate buffer, hydrolysis of hemoglobin | Sus scrofa |
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