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Literature summary for 3.4.23.5 extracted from
- Cathepsins (1970), Methods Enzymol., 9, 285-315.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3-phenylpyruvate | - |
Oryctolagus cuniculus |  |
| dithioerythritol | - |
Oryctolagus cuniculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | 52000 | gel filtration | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Gallus gallus | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Gallus gallus |
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
| liver | - |
Oryctolagus cuniculus | - |
| muscle | - |
Gallus gallus | - |
| muscle | - |
Oryctolagus cuniculus | - |
| spleen | - |
Bos taurus | - |
| spleen | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.101 | - |
- |
Gallus gallus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, pH 3-4 or at pH 8, stable for several days | Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Albumin + H2O | serum albumin | Oryctolagus cuniculus | ? | - |
? | |
| Hemoglobin + H2O | - |
Gallus gallus | ? | - |
? | |
| Hemoglobin + H2O | denatured hemoglobin | Bos taurus | ? | - |
? | |
| Hemoglobin + H2O | denatured hemoglobin | Oryctolagus cuniculus | ? | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
- |
Bos taurus |
| 60 | - |
40 min, comlete loss of activity | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 2.8 | 3 | - |
Gallus gallus |
| 2.8 | 3 | - |
Bos taurus |
| 2.8 | 3 | denatured hemoglobin | Oryctolagus cuniculus |
| 4 | - |
- |
Gallus gallus |
| 4 | - |
- |
Bos taurus |
| 4 | - |
serum albumin | Oryctolagus cuniculus |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 2.5 | - |
inactivation below | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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