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Literature summary for 3.4.23.5 extracted from

  • Agarwal, N.; Rich, D.H.
    An improved cathepsin-D substrate and assay procedure (1983), Anal. Biochem., 130, 158-165.
    View publication on PubMed
Search for more literature for 3.4.23.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0071
-
 Phe-Ala-Ala-(4-nitro)Phe-Phe-Val-Leu-4-hydroxymethylpyridine ester
-
 Sus scrofa
0.033
-
 Phe-Gly-Gly-(4-nitro)Phe-Phe-Val-Leu-methyl ester
-
 Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 pig
-

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 assay procedure Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phe-Ala-Ala-(4-nitro)Phe-Phe-Val-Leu-4-hydroxymethylpyridine ester + H2O
-
 Sus scrofa ?
-
 ?
Phe-Gly-Gly-(4-nitro)Phe-Phe-Val-Leu-methyl ester + H2O
-
 Sus scrofa ?
-
 ?

Subunits

Subunits Comment Organism
?
-
 Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.6
-
 Phe-Gly-Gly-(4-nitro)Phe-Phe-Val-Leu-methyl ester
-
 Sus scrofa
2.9
-
 Phe-Ala-Ala-(4-nitro)Phe-Phe-Val-Leu-4-hydroxymethylpyridine ester
-
 Sus scrofa