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Literature summary for 3.4.23.48 extracted from

  • Kukkonen, M.; Lahteenmaki, K.; Suomalainen, M.; Kalkkinen, N.; Emody, L.; Lang, H.; Korhonen, T.K.
    Protein regions important for plasminogen activation and inactivation of a2-antiplasmin in the surface protease Pla of Yersinia pestis (2001), Mol. Microbiol., 40, 1097-1111.
    View publication on PubMed
Search for more literature for 3.4.23.48

Protein Variants

Protein Variants Comment Organism
D206A 1.3% of wild-type plasminogen activation Yersinia pestis
D212R 111% of wild-type plasminogen activation Yersinia pestis
D84A 3.7% of wild-type plasminogen activation Yersinia pestis
D86A 3.5% of wild-type plasminogen activation Yersinia pestis
D97A 56% of wild-type plasminogen activation Yersinia pestis
E217S 52% of wild-type plasminogen activation Yersinia pestis
F215Y 42% of wild-type plasminogen activation Yersinia pestis
H101V 0.8% of wild-type plasminogen activation Yersinia pestis
H108V 121% of wild-type plasminogen activation Yersinia pestis
H203V 109% of wild-type plasminogen activation Yersinia pestis
H208V 1.7% of wild-type plasminogen activation Yersinia pestis
H28V 125% of wild-type plasminogen activation Yersinia pestis
H98V 94% of wild-type plasminogen activation Yersinia pestis
K218A 103% of wild-type plasminogen activation Yersinia pestis
K240A 151% of wild-type plasminogen activation Yersinia pestis
K249A 132% of wild-type plasminogen activation Yersinia pestis
K254A 90% of wild-type plasminogen activation Yersinia pestis
K262A 85% of wild-type plasminogen activation Yersinia pestis
K280A 98% of wild-type plasminogen activation Yersinia pestis
L213I 123% of wild-type plasminogen activation Yersinia pestis
M210G 58% of wild-type plasminogen activation Yersinia pestis
R211K 11% of wild-type plasminogen activation Yersinia pestis
S267A 108% of wild-type plasminogen activation Yersinia pestis
S77A 133% of wild-type plasminogen activation Yersinia pestis
S99A 1% of wild-type plasminogen activation Yersinia pestis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
human alpha2-antiplasmin + H2O Yersinia pestis
-
 fragments of alpha2-antiplasmin
-
 ?

Organism

Organism UniProt Comment Textmining
Yersinia pestis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
human alpha2-antiplasmin + H2O
-
 Yersinia pestis fragments of alpha2-antiplasmin
-
 ?

Subunits

Subunits Comment Organism
More Pla occurs in 3 processed forms of alpha-Pla, beta-Pla and gamma-Pla, of which alpha-Pla with an apparant molecular mass of 37000 Da, corresponds to full-size mature Pla, and beta-Pla and gamma-Pla with molecular weights of 31000 Da and 35000 Da respectively, are thought to result from processing of alpha-Pla, beta-Pla may result from an autoprocessing event Yersinia pestis