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Literature summary for 3.4.23.46 extracted from

  • Drott, J.; Desire, L.; Drouin, D.; Pando, M.; Haun, F.
    Etazolate improves performance in a foraging and homing task in aged rats (2010), Eur. J. Pharmacol., 634, 95-100.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
etazolate i.e. 1-ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester, stimulates alpha-secretase activity Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
amyloid precursor protein + H2O Rattus norvegicus
-
neurotrophic soluble amyloid precursor protein + ?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid precursor protein + H2O
-
Rattus norvegicus neurotrophic soluble amyloid precursor protein + ?
-
?

Synonyms

Synonyms Comment Organism
alpha-secretase
-
Rattus norvegicus