Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
amyloid precursor protein + H2O | Homo sapiens | amyloid precursor protein is cleaved at the N-terminus of Abeta by beta-secretase yielding a slightly shorter soluble APPbeta fragment and a slightly longer CTFbeta fragment (also termed C99) | fragments of amyloid precursor protein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
amyloid precursor protein + H2O | amyloid precursor protein is cleaved at the N-terminus of Abeta by beta-secretase yielding a slightly shorter soluble APPbeta fragment and a slightly longer CTFbeta fragment (also termed C99) | Homo sapiens | fragments of amyloid precursor protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE1 | - |
Homo sapiens |
beta-secretase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | depletion of mu4 by RNAi does not alter the distribution of beta-secretase (BACE1) | additional information |