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Literature summary for 3.4.23.46 extracted from
- Lack of evidence to support the association of polymorphisms within the alpha- and beta-secretase genes (ADAM10/BACE1) with Alzheimers disease (2011), Neurobiol. Aging, 32, 541-543.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | genotyping of 11 single nucleotide polymorphisms covering the complete BACE1 gene reveals no single-marker or haplotypic association with Alzheimer's disease. Neither ADAM10 coding for alpha-secretase nor BACE1 present with any evidence to suggest that they are major candidate genes involved in conferring risk for Alzheimer's disease | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | genotyping of 11 single nucleotide polymorphisms covering the complete BACE1 gene reveals no single-marker or haplotypic association with Alzheimer's disease. Neither ADAM10 coding for alpha-secretase nor BACE1 present with any evidence to suggest that they are major candidate genes involved in conferring risk for Alzheimer's disease | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
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Release 2023.1 (January 2023)
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