Literature summary for 3.4.23.46 extracted from

Ghosh, A.K.; Bilcer, G.; Harwood, C.; Kawahama, R.; Shin, D.; Hussain, K.A.; Hong, L.; Loy, J.A.; Nguyen, C.; Koelsch, G.; Ermolieff, J.; Tang, J.
Structure-based design: potent inhibitors of human brain memapsin 2 (beta-secretase) (2001), J. Med. Chem., 44, 2865-2868.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	strategies for inhibitor design	Homo sapiens
OM99-2	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Homo sapiens	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000001	-	OM99-2	memapsin 2	Homo sapiens

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Release 2023.1 (January 2023)