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Literature summary for 3.4.23.45 extracted from

  • Stuetzer, I.; Selevsek, N.; Esterhazy, D.; Schmidt, A.; Aebersold, R.; Stoffel, M.
    Systematic proteomic analysis identifies beta-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic beta-cells (2013), J. Biol. Chem., 288, 10536-10547.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JL18
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Source Tissue

Source Tissue Comment Organism Textmining
MIN-6 cell
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Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information screen for substrate proteins in pancreatic beta cells by proteomic approach reveals non-redundant roles of BACE1 and BACE2 in ectodomain shedding, with BACE1 regulating a broader and BACE2 a more distinct set of beta-cell-enriched substrates including two proteins of the seizure 6 protein family, SEZ6L and SEZ6L2 Mus musculus ?
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