Literature summary for 3.4.23.39 extracted from

Kiso, A.; Hidaka, K.; Kimura, T.; Hayashi, Y.; Nezami, A.; Freire, E.; Kiso, Y.
Search for substrate-based inhibitors fitting the S2 space of malarial aspartic protease plasmepsin II (2004), J. Pept. Sci., 10, 641-647.

Search for more literature for 3.4.23.39

Application

Application	Comment	Organism
medicine	plasmepsin is an important target for the development of antimalarial drugs, since its inhibition leads to the starvation of Plasmodium falciparum	Plasmodium falciparum

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	plasmepsin is an important target for the development of antimalarial drugs, since its inhibition leads to the starvation of Plasmodium falciparum. A series of substrate-based dipeptide-type plasmepsin II inhibitors containing the hydroxymethylcarbonyl isostere as a transition-state mimic are synthesized	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	-	-	-

Synonyms

Synonyms	Comment	Organism
malarial aspartic protease	-	Plasmodium falciparum

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Release 2023.1 (January 2023)